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Detailed Information on BDNF ELISA

The ELISA or enzyme-linked immunosorbent assay is a popular tool used for measuring and identifying proteins and antigens from samples. Target-specific ELISA kits are available from a number of manufacturers and will help enhance your immune-detection experiments.

Brain-derived neurotrophic factor or BDNF is also known as abrineurin is a protein that is encoded from the BDNF gene. BDNF is a part of the neurotrophin family that is linked to the canonical nerve growth factor. You can know more about BDNF ELISA at


Neurotrophic factors are observed in the mind as well as the periphery. BDNF can also be expressed from the retina, kidneys, prostate, motor nerves, and lean muscle, and can also be located in saliva. BDNF is created from the endoplasmic reticulum and secreted out of dense-core vesicles. 

Other attributes include sensory neuron losses which affect balance, coordination, hearing, taste, and breathing.  Knockout mice also exhibit cerebellar abnormalities and an increase in the number of sympathetic neurons. Certain kinds of physical exercise can increase BDNF synthesis in the body.

It is a phenomenon that's partially accountable for exercise-induced neurogenesis and developments in cognitive functioning. BDNF is broadly expressed in the central nervous system also functions in an autocrine and paracrine manner on many types of neurons.

BDNF promotes neuronal survival and differentiation and has been proven to play a crucial role in memory formation and synaptic regulation. BDNF is triggered by cortical neurons and is vital for the survival of striatal neurons within the mind. Expression of BDNF is decreased in Alzheimer's and Huntington patients.